STAT1 and osteoporosis: And the study of Zhang et al. (2021a) indicated that bone marrow mesenchymal stem cells-derived exosomes (BMSCs-Exos) can also reduce the osteoporosis in rats by delivering miR-935 to osteoblasts and targeting signal transducer and activator of transcription 1 (STAT1), inhibiting its expression, and promoting the proliferation and differentiation of osteoblasts.