Inflammatory markers such as interleukin-6 (IL-6), interferon-γ (IFN-γ), and tumour necrosis factor-α (TNF-α) were found to be significantly higher in first-episode psychosis patients than in controls (Flatow et al., 2013; Ding et al., 2014; Fraguas et al., 2019), whereas brain-derived neurotrophic factor (BDNF) levels were found to be lower in first-episode SCZ patients (ShoshinaHovis et al., 2021). The gene discussed is BDNF; the disease is psychotic disorder.