Initial PBX1 is associated with cancers of the hematopoietic system (Shimabe et al., 2009), which are followed by solid tumors such as neuroblastoma (Veselska et al., 2019), renal carcinoma (Wei et al., 2018; Wang et al., 2022b), gastric cancers (He et al., 2017), and esophageal cancers (Zhu et al., 2017). The gene discussed is PBX1; the disease is renal carcinoma.