Primary cilia mediate cancer-related signaling such as the Sonic hedgehog, Wingless/INT (Wnt), NOTCH, platelet-derived growth factor (PDGF), mammalian target of rapamycin (mTOR), and Hippo pathways (Basten and Giles, 2013; Liu et al., 2018; Fabbri et al., 2019). The gene discussed is MTOR; the disease is cancer.