NBP can stably bind <i>ALB, ESR1, EGFR, HSP90AA1</i>, and other targets, and may play a role in neuroprotection for patients with DEACMP by modulating Lipid and atherosclerosis, <i>IL-17</i> signaling pathway, <i>MAPK</i> signaling pathway, <i>FoxO</i> signaling pathway, <i>PI3K/AKT</i> signaling pathway. Here, ESR1 is linked to atherosclerosis.