Moreover, when comparing ICI classes, anti-CTLA-4 and anti-PD-1 classes were associated with a lower likelihood of reporting peripheral neuropathy compared to anti-PDL-1 (ROR 0.510; 95% CI 0.267-0.966; p=0.03; ROR 0.533; 95% CI 0.31-0.907; p=0.016, respectively). Here, PDCD1 is linked to peripheral neuropathy.