Within a week of infection, robust Spike-directed antibodies were elicited (S-IgG: 49.50 (13.51, 134.37 BAU/ml; S-IgM: 56.61, IQR 23.20, 154.91ng/ml; and S-IgA: 157.63 (40.83, 676.58 BAU/ml), with levels peaking between 25 and 37 days (S-IgG: 4612; 1569-12947 ng/ml and S-IgM 2264.35 (1033.15, 5346.98 ng/ml). Here, CD40LG is linked to infection.