found that lncSNHG1 was induced in the CD4+ tumor infiltrating lymphocyte(TIL), thereby sponging miR-448 to increase the expression of indoleamine 2,3-dioxygenase (IDO) and Foxp3 to regulate the differentiation of Treg cells and affect the immune escape of breast cancer (96). This evidence concerns the gene CD4 and neoplasm.