IFNG and eosinophilic esophagitis: In summary, increased frequency of various Th2 markers in biopsy, but also of Th17 and ILC1-IFNγ+ cells and of a large panel of soluble factors underlined the complexity of EoE pathology, with involvement of various immune actors far beyond a simplistic T2 immune response, as recently observed for severe asthma (25).