IL1B and eosinophilic esophagitis: In parallel with T2 markers, high local inflammation was confirmed in the biopsies from EoE patients, with increased levels of IFNβ, IL-1β, CCL1/13/22, CXCL1/2/6/12/13, and MMP1/2, for which some were already shown to be upregulated at the mRNA level (6).