The results revealed that pdcd1lg2 expression was positively related with the expressions of CXCL13, CXCL11, CXCL10, CCL8, CCL5, CCL4, and CCL3 which are chemokines, and CXCR6, CCR5, CCR4, CCR2 and CCR1 which are chemokine receptor molecules, and was negatively associated with the expressions of other chemokines such as CXCL5, CXCL17, CXCL1, CX3CL1, CCL28, CCL15 and CCL14, and other chemokine receptor such as CXCR4, CXCR2, CXCR1, CX3CR1, CCR10, and CCR9 in some types of cancer. The gene discussed is CX3CL1; the disease is cancer.