Compared to the negative control group (NC), DNMT1 protein levels were decreased in HepG2-SR and HCCLM3-SR cells but slightly increased in Huh7-SR cells upon MenSC treatment; TET1 protein levels were upregulated in HCCLM3-SR cells but not altered in HepG2-SR and Huh7-SR cells after MenSC treatment; and the TET2 protein levels were upregulated by MenSCs in all three HCC-SR cell lines (Fig. 6C). This evidence concerns the gene DNMT1 and hepatocellular carcinoma.