As we have shown that BNIP3 and BNIP3L levels were decreased in HCC-SR cells (Fig. 1C) and that promoter hypermethylation was responsible for the inhibition of BNIP3 and BNIP3L transcription in HCC-SR cells in previous subsections (Fig. 1D, E), we further explored whether these molecules were upregulated by MenSCs in HepG2-SR and Huh7-SR cells through DNA demethylation. This evidence concerns the gene BNIP3L and hepatocellular carcinoma.