This is consistent with the results of whole-exome studies by Anglesio 2017 and Suda 2018, which detected somatic driver mutations at the DNA level in the PIK3CA gene in the epithelium of DIE lesions [15] and in the epithelium of ovarian endometriosis, as well as in the eutopic endometrium of healthy patients [17], among others. The gene discussed is PIK3CA; the disease is ovarian endometriosis.