Finally, abundances of 3 (for PELO, CLK3, and CISH) of the 27 autoantibodies were significantly correlated with CDAI in all RA patients (n = 62), with a subset of those already found to be significant in the ACPA+ RA (for PELO) and ACPA− RA (for CLK3) subgroups. The gene discussed is PRTN3; the disease is rheumatoid arthritis.