Given that type I IFN is a primary pathogenic factor in SLE regardless of ancestral background, additional analyses, including an examination of pathways predicted from summary AsA GWAS, differential gene expression from AsA whole-blood samples and GSVA enrichment of interferon gene signatures in AsA patients confirmed the well-established association between SLE and IFN across ancestral populations. The gene discussed is IFNA1; the disease is systemic lupus erythematosus.