As previously observed in surgical liver samples from patients with cirrhosis18, MAIT cells, identified by their Vα7.2 positivity by immunostaining, were found in proximity to fibrogenic smooth muscle alpha-actin (α-SMA) positive myofibroblasts in PCLS from patients with fibrosis or cirrhosis (Fig. 1b). Here, ACTA1 is linked to fibrosis.