Indeed, deregulated pathways (“Malaria”, “Hepatitis B”, “Leishmaniasis”, “NOD-like receptor signaling pathway”, “TNF signaling pathway” and “Measles”) were all related to inflammatory signaling but mainly included genes of the KEGG “apoptosis” or “autophagy” pathways (Atg5, Bcl2, Birc3, Akt2... Fig. 4c, d). The gene discussed is AKT2; the disease is hepatitis B virus infection.