Though the mRNA level of PRMT1 in colon cancer tissues tended to be higher than that in cancer adjacent tissues (Fig. S6A), the high PRMT1 expression in the colon cancer tissues was associated with the longer patient survival (Fig. 6A), supporting a role of PRMT1 in preventing the tumor malignancy. The gene discussed is PRMT1; the disease is malignant colon neoplasm.