As a first analysis, we trained a prediction model, only providing cytokines data as features and we observed that obstructive CAD associates with high concentrations of IL-1β, IL-12, IL-33, IL-10, IFN-γ, and MCP-1, while non-obstructive CAD is more likely to associate with high levels of IL-23, IFN-α2, IL-18, IL-8, IL-6, TNF-α and IL-17a. This evidence concerns the gene CXCL8 and coronary artery disorder.