IL10 and inflammatory bowel disease: Interestingly, SFB were absent in ileal and colonic mucosal biopsies from IBD patients with active or inactive disease To test the capability of human gut microbiota to drive inflammation in TnfΔARE mice as we and others showed previously using Il-10-deficient mice [15, 80], we colonized TnfΔARE mice with fecal microbiota derived from an IBD patient.