According to the cibersort method, the low-risk patients harbored significantly larger proportions of CD8 T cells and dendritic-resting cells (TCGA HBV–related HCC dataset: P = 0.039, P = 0.024, respectively; Gao et al. dataset: P = 0.00018, P = 0.0057). The gene discussed is CD8A; the disease is hepatocellular carcinoma.