Two recent studies have shown that circNfix and RNA circ_0001006 can alleviate and promote myocardial hypertrophy in mice by targeting the miR‐145‐5p/activating transcription factor 3 (ATF3) and miR‐214‐3p/PAK6 pathways, respectively.103, 104. This evidence concerns the gene ATF3 and cardiac hypertrophy.