These analyses indicated that the survival associations of PD-1+ T cells did not statistically significantly differ according to the density of PD-L1+ macrophages or PD-L1 expression in tumour cells in univariable (Supplementary Fig. S11, Supplementary Tables S10, S11) or multivariable analyses (Supplementary Tables S10, S11) (all Pinteraction > 0.005). This evidence concerns the gene PDCD1 and neoplasm.