Curiously, the increase in the frequency of DAF-FM+ cells during 24h macrophage infection induced by arg+/spm+ negative correlates with Nos2 levels (Corr -0.925, p < 0.05) and Nos2 levels negatively correlate with NO production per cell (MFI; Corr -0.929, p < 0.05) (Fig 3B and 3C, S7 Fig). Here, NOS2 is linked to infection.