Despite FGFR3 inhibiting key components of the adaptive immune response, including lymphocyte infiltration and CD8A T-cell expression [33], our findings revealed that WT FGFR3 in BUC tissues promote the infiltration of tumor immune cells such as CD8+ T cells, macrophages, and dendritic cells, compared to mutated FGFR3. Here, FGFR3 is linked to neoplasm.