STAT3 and glioblastoma: To further determine the underlying mechanism of GALNT2 overexpression in GBM and GSCs, bioinformatics analysis was conducted to predict the potential transcription factors that transcriptionally activate GALNT2 expression, and it was observed that there are four potential DNA binding sites for STAT3 binding in the JASPAR database (http://jaspar.binf.ku.dk/) (data not shown).