Table 5 shows that the 6 Highly Cited Papers are “Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009,”[19] “Update on the use of immunoglobulin in human disease: A review of evidence,”[20] “Outcomes Following Gene Therapy in Patients With Severe Wiskott-Aldrich Syndrome,”[21] “Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects,”[22] “From IPEX syndrome to FOXP3 mutation: a lesson on immune dysregulation,”[23] and “Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency.”[24]. This evidence concerns the gene FOXP3 and combined immunodeficiency.