The results showed that the target genes of the intersection of Jiaotai Pill and T2DM were enriched in the advanced glycation end products (advanced glycation end product [AGE] − RAGE signaling pathway, phosphoinositide 3-kinase [PI3K]/AKT (protein kinase B) signaling pathway, endocrine resistance pathway, tumor necrosis factor (TNF) signaling pathway and Toll-like receptor signaling pathway are shown in Figure 6. This evidence concerns the gene TNF and type 2 diabetes mellitus.