There were also 2 genes (KCNH7 and TMEM215) that belong to the DFNA16 (Deafness, autosomal dominant 16: Fukushima et al., 1999) and DFNA47 (Deafness, Autosomal Dominant 47: D’Adamo et al., 2003) loci, respectively, which are critical chromosomal regions associated with deafness whose causative genes are unknown to date. The gene discussed is TMEM215; the disease is deafness.