Five of the genes identified were reported to carry mutations that cause hearing-related mouse phenotypes in the Mouse Genome Informatics (MGI) database: Gata3, Kcnq4, Gabra5, Hcn1, and Kit. In the Online Mendelian Inheritance in Man (OMIM) database, 3 human orthologous were associated with deafness or hearing loss (GATA3, KCNQ4 and KIT). The gene discussed is KCNQ4; the disease is hearing loss disorder.