CYFIP2 and Intellectual disability: The two members of the cytoplasmic FMR1-interacting protein family, CYFIP1 and CYFIP2, are evolutionarily conserved proteins whose genetic variants are causally associated with numerous brain disorders, including autism spectrum disorders, intellectual disability, schizophrenia, and epilepsy (Schenck et al. 2001; Abekhoukh and Bardoni 2014; Zhang, Lee, et al. 2019).