To explore the functional role of PRMT5 in ovarian cancer, we generated PRMT5 stable knockdown cell line by specific short hairpin RNAs (shRNAs), and found that knockdown PRMT5 dramatically decreased A2780, A2780‐Taxol, OV2008, and C13* cells proliferation by colony formation assay and cell number counting assay (Figure 1E and F and Figure S1G). Here, PRMT5 is linked to ovarian cancer.