Moreover, the top 10 KEGG pathways that might be regulated by GTSE1 were clustered and are shown in Figure 6D, including the cell cycle, cytokine‒cytokine receptor interaction, oocyte meiosis, P53 signaling pathway, DNA replication, human T-cell leukemia virus one infection, Th17-cell differentiation, T-cell receptor signaling pathway, primary immunodeficiency, and base excision repair. This evidence concerns the gene TP53 and inborn error of immunity.