The target genes of the circ-YOD1-miR-21–3p/miR-296–3p axis are BCL6, FBXL18, MMP9, and FCGR3B, as confirmed in other studies describing associations of MMP9, BCL6 (32, 33), hsa-miR-21–3p (32), and hsa-miR-296–3p (34) with CHD. This evidence concerns the gene MMP9 and coronary artery disorder.