Similarly, the innate IS is related to the recognition, processing, and destruction of pathogens in the body (Nicholson, 2016); however, it has also been associated with the development and progression of MS, antigen-presenting cells (APCs), and proinflammatory cytokines, such as IL-1α, IL-1β, and IL-6, considered as the main mediators of signal pathways related to the BBB disruption (Jara et al., 2006; Chastain et al., 2011). The gene discussed is IL6; the disease is myeloid sarcoma.