Changes in blood biomarker levels during antitubercular treatment in either PTB or EPTB cases have been previously reported in a number of prospective studies [16, 47–50], showing the normalization of several inflammatory markers (such as CRP, IP-10, CCL1, IFN-γ, and TNF-α) after successful TB treatment. The gene discussed is CXCL10; the disease is tuberculosis.