The following medications are currently Food and Drug Administration (FDA) approved for the treatment of sleep disorders: benzodiazepines and non-benzodiazepine hypnotics, tricyclic antidepressants, therapeutic drugs that target orexin/hypocretin receptors, and off-label use of medications such as other antidepressants, antihistamines, herbal preparations, and antipsychotics (50–52). Here, HCRT is linked to sleep disorder.