LASSO regression model of HCC patients showed that the best number of ICD associated prognosis genes in the model was 6, which were BAX, CASP8, IFNB1, LY96, NT5E and PIK3CA, and the formula was risk scores = gene expression of BAX*0.1738 + gene expression of CASP8*0.1628 + gene expression of IFNB1*0.5482 + gene expression of LY96*0.0646 + gene expression of NT5E*0.1006 + gene expression of PIK3CA*0.0723 (Figures 7B, C). Here, IFNB1 is linked to hepatocellular carcinoma.