Cancer was a significant touchstone in the contextualization process: “There's [sic] certain cancers that kind of run in the family, you know I've had breast cancer, lung cancer you know things like that so it was like you know, is this, you know is this something that's going to happen to me?” (patient 4), and “I'm BRCA2, I'm always going to be concerned about anything now with cancer, after what I just went through with my breast cancer” (patient 18). The gene discussed is BRCA2; the disease is breast carcinoma.