In CC cells and renal cancer cells, miR-182-5p directly binds to the 3’-UTR of FBXW7 mRNA and inhibits the expression of wild-type FBXW7 proteins because FBXW7 contains a hypothesized binding site for miR-182-5p in its 3’-UTR (79, 80). Here, FBXW7 is linked to cholangiocarcinoma.