EPHA2 and lung adenocarcinoma: In order to investigate the relevance of EphA2 for basal and IR-induced lung tumor cell migration, a Boyden-chamber transwell migration assay was developed with NCI-H358 lung adenocarcinoma cells, stably transduced with a doxycycline-inducible EphA2-directed shRNA (shEphA2) vector or an inducible scramble shRNA (shScr) expression vector (Figure S1A).