The remaining IDH-wildtype anaplastic astrocytomas (13/39) and IDH-wildtype diffuse astrocytomas (7/26) were reclassified as pediatric-type diffuse astrocytoma, MYB- or MYBL1-altered or high-grade diffuse glioma, H3- and IDH-wildtype. Here, IDH1 is linked to diffuse astrocytoma.