The alterations in FGFR4, KIT, and PEG3 were correlated with a short OS in astrocytoma, alterations in CDK4, FUBP1, and NTRK2 were correlated with a short OS in oligodendroglioma, and alterations in CDK4, CIC, FGFR3, and KMT5B were correlated with a short OS in glioblastoma. This evidence concerns the gene KMT5B and astrocytoma (excluding glioblastoma).