PSMD2 and esophageal squamous cell carcinoma: Consistent with the conclusion that ASS1 mediates the PSMD2-dependent inhibition of autophagy, we found that silencing ASS1 expression in cells with PSMD2 overexpression reversed the phenotype of increased proliferation and colony formation of ESCC cells (Fig. 5A–D Additional file 1: Fig. S6A).