Nevertheless, as the advance of molecular biology technique, especially next-generation sequencing applying for the pathological diagnosis, numerous novel characteristic molecules involving neoplastic diagnosis have been unearthed and thus refined many tumor entities in mesenchymal tumor, such as HEY1-NCOA2 fusion in mesenchymal chondrosarcoma [2], EWSR1-NR4A3 fusion in extraskeletal myxoid chondrosarcoma [3], WWTR1-CAMAT1 fusion and YAP1-TFE3 fusion in epithelioid hemangioendothelioma [4, 5]. Here, EWSR1 is linked to neoplasm.