We also found that Mfn2 deposition occurred in two different ways: granular deposition or deposition along the GBM at the same time (Fig. 1B) We also detected Mfn2 expression in five DKD and five membranous nephropathy (MN) patients as disease controls, and five precancerous tissues from kidney tumors served as normal controls. The gene discussed is MFN2; the disease is membranous glomerulonephritis.