EGFR and congenital rubella syndrome: The MTD of unmasked EGFR-TCE (48-h continuous i.v. infusion) was 33 μg kg−1 d−1; a 1-h i.v. infusion of 8 μg kg−1 followed by continuous infusion of 66 μg kg−1 d−1 (terminated after 25 h) resulted in severe CRS-associated toxicities.