MYC occupation was generally accompanied by higher enhancer activity and chromatin accessibility as revealed by 22Rv1 H3K27ac ChIP-Seq and PCa ATAC-Seq data, but also indicated higher CTCF binding in 22Rv1 cells and cohesin binding in A549 cells at H3K27ac- CTCF sites (Fig. 3g and S4k). This evidence concerns the gene CTCF and posterior cortical atrophy.