Regarding type I interferon, we observed differences in IFN-α2 levels among groups (H = 12.21, p = 0.002, \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$${\eta}_{H}^{2}\,$$\end{document}ηH2= 0.063), specifically a significant reduction of IFN-α2 in PASC patients comparing to both non-PASC and the HC (p = 0.004 for both comparations; Fig. 5A). The gene discussed is IFNA2; the disease is long COVID-19.