C-reactive protein (CRP) is widely used as a clinical parameter to measure inflammatory status, and numerous observational studies have reported associations between elevated CRP levels and the risk of colorectal cancer (CRC) incidence [1,2], population mortality due to CRC [3,4], and the clinical prognosis of CRC patients, including death [5,6], metastasis [5,7], postoperative complications [8,9], and recurrence [5,10,11]. The gene discussed is CRP; the disease is colorectal carcinoma.