According to the forest plot, upregulation of NCAPG expression in cancer tissues was related to worse OS regardless of the group (respiratory cancer, HR = 2.27, 95% CI = 1.73–2.98, P < 0.00001; digestive cancer, HR = 2.12, 95% CI = 1.39–3.22, P = 0.0005; breast cancer, HR = 7.57, 95% CI = 3.13–18.30, P < 0.00001; glioma, HR = 9.34, 95% CI = 3.75–23.26, P < 0.00001). This evidence concerns the gene NCAPG and central nervous system cancer.