For serum IgA, there was a significant association between COVID-19 severity and binding intensity for the Npro Full Ecoli, S1Frag Ecoli, S2Frag Ecoli, S2Pri Ecoli, Spro Ecoli, S1 Full HEK and S1 Sf21 (Fig 4 and S6 and S7 Tables). The gene discussed is CD79A; the disease is COVID-19.