These proteins include NECTIN-1, NFASC, and GRID1 (a.k.a. GluD1) with important roles in cell adhesion, axon-glial contacts, synapse formation, and neurotransmission (38, –40), highlighting their potential roles in the demyelinating neurodegenerative pathologies seen in Krabbe disease. Here, NFASC is linked to Krabbe disease.