IL5 and acute chest syndrome: At baseline, for children with ACS, IL5 (ACS, 0.59 [-0.41, 1.89] vs non-ACS, 0.34 [-0.31, 1.11], p = 0.028) and IL-13 (ACS 1.01 [0.05, 2.03] vs non-ACS: 0.05 [0.05, 1.65], p = 0.024) levels were higher (Fig 1).